This antibody recognises interferon beta (IFN-beta), a 22 kDa member of the type I alpha/beta interferon family. IFN beta, initially described as fibroblast interferon, is produced predominantly by fibroblasts and some epithelial cells. Type 1 interferons are produced primarily in response to viral infections as part of the host immune response and can also inhibit the development of tumors. IFN-beta is involved in the regulation of non-specific humoral immune responses and responses against viral infections.
Applications
WB, IHC-P
Dilutions
WB: 5 µg/ml
Reactivity
Human, Mouse
Immunogen
A peptide corresponding to 17 amino acids near the centre of human IFN Beta.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
1 mg/ml
Molecular Weight
Approximately 15 kDa in A20 cell lysates.
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti Human interferon beta antibody recognizes interferon beta (IFN-beta), a 22 kDa member of the type I alpha/beta interferon family. IFN beta, initially described as fibroblast interferon, is produced predominantly by fibroblasts and some epithelial cells. Type 1 interferons are produced primarily in response to viral infections as part of the host immune response and can also inhibit the development of tumors. IFN-beta is involved in the regulation of non-specific humoral immune responses and responses against viral infections.