Anti-Interferon alpha 2 Antibody [N27] (A248919)

Anti-Interferon alpha 2 Antibody [N27]

Mouse monoclonal [N27] antibody to Interferon alpha 2.

This antibody recognizes a protein of 16-27kDa, identified as human interferon-II) (IFN-(II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This MAb is specific for IFN-(II) and does not cross-react with IFN-(I). The site recognized by this MAb is called site I and is responsible for the antiviral and anti-proliferative activities of IFN-(II). Epitopes of N27 and N39 MAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.

ELISA, Blocking, Flow Cytometry, IF

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Human

Recombinant human IFN alpha 2.

Mouse

Monoclonal

N27

IgG1

Unconjugated

Protein A/G chromatography.

200 µg/ml

16-27 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Interferon alpha 2 Antibody [N27] - BSA and Azide free (A252099).

Alpha 2a interferon, IFN alpha 2, IFN alphaA, IFN-alpha-2, IFNA, Ifna2, IFNA2B, IFNA2_HUMAN, INFA2, Interferon, Interferon alpha 2a, Interferon alpha 2b, Interferon alpha A, Interferon alpha-2, Interferon alpha-A, LeIF A, LeIFA, MGC125764, MGC125765