Anti-Insulin Antibody [E2-E3 + 2D11-H5] - BSA and Azide free (A252220)

Mouse monoclonal [E2-E3 + 2D11-H5] antibody to Insulin for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Insulin Antibody [E2-E3 + 2D11-H5] - BSA and Azide free
Description
Mouse monoclonal [E2-E3 + 2D11-H5] antibody to Insulin.
Specificity
This antibody recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human, Bovine, Porcine, Rabbit, Mouse
Immunogen
Purified pig insulin, conjugated to KLH.
Host
Mouse
Clonality
Oligoclonal
Clone ID
E2-E3 + 2D11-H5
Isotype
IgG1, kappa + IgG1, kappa
Conjugate

Unconjugated

Concentration
1 mg/ml
Molecular Weight
6 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes

Please note, this product is an oligoclonal antibody; it is a cocktail of monoclonal antibodies that have been carefully selected. Oligoclonal antibodies not only have the specificity and batch-to-batch consistency of a monoclonal antibody, but they also have the advantage of the sensitivity of a polyclonal antibody due to their ability to recognize multiple epitopes on an antigen. This antibody is also known as Clone INS04 + INS05.

This oligoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Insulin Antibody [E2-E3 + 2D11-H5] (A249040).

Synonyms
IDDM, IDDM1, IDDM2, ILPR, ins, Insulin A chain, Insulin B chain, INS_HUMAN, IRDN, MODY10, Preproinsulin, Proinsulin, Proinsulin precursor
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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