Recombinant Anti-Inhibin alpha Antibody [rINHA/6919] (A277895)

Anti-Inhibin alpha Antibody [rINHA/6919]

Recombinant mouse monoclonal [rINHA/6919] antibody to Inhibin alpha.

It recognizes a 47kDa protein, which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same α subunit, covalently linked to 1 of 2 distinct subunits, β-α or β-β. Originally isolated from ovarian follicular fluid and characterized as a disulphide-linked dimeric glycoprotein, inhibin belongs to the transforming growth factor β (TFGβ) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity. Inhibin antibody is also used to make the differential diagnosis of intra-uterine vs. ectopic pregnancy in endometrial curetting.

IHC-P: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 233-362, of human Inhibin alpha protein. The exact sequence is proprietary.

Mouse

Monoclonal

rINHA/6919

IgG1

Unconjugated

Protein A/G chromatography.

200 µg/ml

47 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Inhibin alpha Antibody [rINHA/6919] - BSA and Azide free (A278483).

A inhibin subunit, A inhibin subunit precursor, AW55578, IHA, inhA, INHA_HUMAN, Inhibin alpha chain, Inhibin alpha chain precursor, Inhibin alpha subunit