Anti-IL-5 Antibody [IL5/4161] - BSA and Azide free (A278259)

Mouse monoclonal [IL5/4161] antibody to IL-5 for Flow Cytometry and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-IL-5 Antibody [IL5/4161] - BSA and Azide free
Description
Mouse monoclonal [IL5/4161] antibody to IL-5.
Specificity
Interleukin-5, or IL-5, was originally discovered as a soluble T cell-derived factor, called T cell-replacing factor (TRF), that induced T cell-depleted activated B cells to secrete immunoglobulin. Native IL-5 is a disulfide-linked homodimer. IL-5 is initially synthesized as a precursor with a 19 amino acid signal peptide which is cleaved to form a 112 amino acid mature protein. Murine and human IL-5 exhibit 70% sequence identity at the amino acid level. IL-5 exerts its biological activity through the IL-5 receptor (IL-5R), which is composed of at least two chains: an chain that binds IL-5 with low affinity and a chain that does not bind IL-5, but together with the IL-5 a chain, constitutes the high affinity IL-5 receptor. The chain is common to the IL-3, IL-5 and GM-CSF receptors and has been shown to signal through the JAK/Stat pathway.
Applications
Flow Cytometry, IHC-P
Dilutions
Flow Cytometry: 1-2 µg/million cells, IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment corresponding to mature human IL-5 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
IL5/4161
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
17 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-IL-5 Antibody [IL5/4161] (A277671).
Synonyms
B cell differentiation factor I, B-cell differentiation factor I, Colony stimulating factor, Colony stimulating factor eosinophil, EDF , Eosinophil differentiation factor, IL 5, IL5, IL5_HUMAN, Interleukin 5, Interleukin 5 (colony stimulating factor eosinophil), Interleukin 5 (colony stimulating factor, eosinophil), Interleukin-5, Interleukin5, T cell replacing factor, T-cell replacing factor, TRF
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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