Anti-IL-4 Antibody [MP4-25D2] (A281250)

Anti-IL-4 Antibody [MP4-25D2]

Rat monoclonal [MP4-25D2] antibody to IL-4.

This antibody recognises human Interleukin-4 (IL-4), also known as B-cell stimulatory factor 1, Binetrakin, Pitrakinra or Lymphocyte stimulatory factor 1. Interleukin-4 is a 153 amino acid ~17kDa cytokine involved in the activation of B cells, macrophages and monocytes (UniProt: P05112).Polymorphisms in the IL-4 gene are associated with susceptibility to, and outcome of ischemic stroke. Rat anti Human Interleukin-4 antibody, clone MP4-25D2 is reported to neutralize IL-4 activity (Abrams et al. 1992 and Carvalho et al. 1994).

WB, Flow Cytometry, IHC-Fr, ELISA

FC 1: 1:10 - 1:50, WB: 1:500 - 1:1,000, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl

Human, Rhesus Monkey

Purified CHO cell expressed recombinant human IL-4.

Rat

Monoclonal

MP4-25D2

IgG1

Protein G affinity chromatography of tissue culture supernatant.

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rat anti Human Interleukin-4 antibody, clone MP4-25D2 recognizes human Interleukin-4 (IL-4), also known as B-cell stimulatory factor 1, Binetrakin, Pitrakinra or Lymphocyte stimulatory factor 1. Interleukin-4 is a 153 amino acid ~17kDa cytokine involved in the activation of B cells, macrophages and monocytes (UniProt: P05112).Polymorphisms in the IL-4 gene are associated with susceptibility to, and outcome of ischemic stroke (Marousi et al. 2011).Rat anti Human Interleukin-4 antibody, clone MP4-25D2 is reported to neutralize IL-4 activity (Abrams et al. 1992 and Carvalho et al. 1994).

B-cell stimulatory factor 1, Binetrakin, BSF-1, IL4, Interleukin-4, Lymphocyte stimulatory factor 1, Pitrakinra