This antibody recognises human Interleukin-21 (IL-21), also known as Za11. IL-21 is a cytokine with immunoregulatory activity. IL-21 stimulates B- and T-cell proliferation and increases the activity of NK cells and disease-specific cytotoxic T-cells. It might also inhibit dendritic cell activation and maturation during the T-cell mediated immune response.
Applications
WB, IHC-P
Dilutions
IHC-P 1: 5 µg/ml, WB: 0.5 - 1 µg/ml
Reactivity
Human
Immunogen
Synthetic peptide corresponding to 15 amino acid near the centre of human IL-21 precursor.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
500 µg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti Human interleukin-21 antibody recognizes human Interleukin-21 (IL-21), also known as Za11. IL-21 is a cytokine with immunoregulatory activity. IL-21 stimulates B- and T-cell proliferation and increases the activity of NK cells and disease-specific cytotoxic T-cells. It might also inhibit dendritic cell activation and maturation during the T-cell mediated immune response.