Anti-ICAM3 Antibody [186-2G9] (A248906)

Mouse monoclonal [186-2G9] antibody to ICAM3 for IF and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-ICAM3 Antibody [186-2G9]
Description
Mouse monoclonal [186-2G9] antibody to ICAM3.
Specificity
This antibody recognizes the D1 domain of an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (Leucocyte Workshop VI). CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb is excellent for staining of formalin/paraffin tissues.
Applications
IF, IHC-P
Dilutions
IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Stimulated human leukocytes.
Host
Mouse
Clonality
Monoclonal
Clone ID
186-2G9
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
110-160 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes

This antibody blocks binding of CD11a to ICAM-3; order antibody without Sodium Azide!

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-ICAM3 Antibody [186-2G9] - BSA and Azide free (A252086).

Synonyms
CD50, CDW 50, CDw50, ICAM 3, ICAM-3, ICAM-R, ICAM3_HUMAN, ICAMR, Intercellular adhesion molecule 3
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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