Anti-HSV1 Antibody [HSVI/2095] (A250983)

Anti-HSV1 Antibody [HSVI/2095]

Mouse monoclonal [HSVI/2095] antibody to HSV1.

The antibody reacts with HSV type 1 specific antigen. It is suitable for detection of HSV in human cellular material obtained from superficial lesions or biopsies and for the early identification of HSV in infected tissue cultures. The herpes simplex virus (HSV) (also known as cold sore, night fever or fever blister) is a virus that causes a contagious disease. There are two main types of Herpes Simplex Virus (HSV), 1 and 2. The HSV-1 strain generally appears in the orafacial organs. HSV2 usually resides in the sacral ganglion at the base of the spine. All herpes viruses are morphologically identical: they have a large double-stranded DNA genome and the virion consists of an icosahedral nucleo-capsid, which is surrounded by a lipid bilayer envelope. UL42, the processivity subunit of the HSV-1DNA polymerase binds DNA as a monomer and is essential for the replication of the virus. UL42 reduces the rate of dissociation from primer-template DNA, but it does not reduce the rate of elongation. UL42 increases the ability of UL9 to load onto DNA, thus increasing its assembly into a functional complex that is capable of unwinding duplex DNA.

IHC-P: 1-2 µg/ml

Herpes Simplex Virus 1

Baculovirus-expressed HSV DNA polymerase (POL) and POL/UL42 complex.

Mouse

Monoclonal

HSVI/2095

IgG1

Unconjugated

Protein A/G chromatography.

200 µg/ml

61 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-HSV1 Antibody [HSVI/2095] - BSA and Azide free (A254163).

Herpes simplex virus, Herpes simplex virus 1, Herpes simplex virus type 1, HSV 1, Human herpesvirus 1, Human herpesvirus type 1