Anti-HLA G Antibody [MEM-G/1] (A281174)

$480

Mouse monoclonal [MEM-G/1] antibody to HLA G for WB and IHC-P.

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Highlighted products for Anti-HLA G Antibody

Name
Anti-HLA G Antibody [MEM-G/1]
Description
Mouse monoclonal [MEM-G/1] antibody to HLA G.
Specificity
This antibody recognises denatured soluble and membrane-bound HLA G heavy chain.The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region.HLA G belongs to the HLA class I molecules (HLA Class Ib; nonclassical) and is involved in the presentation of foreign antigens to the immune system. This molecule is expressed on the surface of trophoblast cells and plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T lymphocytes, macrophages and mononuclear cells.
Applications
WB, IHC-P
Dilutions
IHC-P 1: 1:60 - 1:100
Reactivity
Human
Immunogen
Denatured bacterially expressed recombinant human HLA G heavy chain.
Host
Mouse
Clonality
Monoclonal
Clone ID
MEM-G/1
Isotype
IgG1
Conjugate

Unconjugated

Purification
Protein A affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Human HLA G antibody, clone MEM-G/1 reacts with denatured soluble and membrane-bound HLA G heavy chain.The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region.HLA G belongs to the HLA class I molecules (HLA Class Ib; nonclassical) and is involved in the presentation of foreign antigens to the immune system. This molecule is expressed on the surface of trophoblast cells and plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T lymphocytes, macrophages and mononuclear cells.
Synonyms
B2 microglobulin, DADB-15K14.8, HLA 6.0, HLA class I histocompatibility antigen alpha chain G, HLA class I histocompatibility antigen, alpha chain G, HLA class I molecule, HLA G antigen, HLA G histocompatibility antigen class I G, HLA G3, HLA-G, HLA-G histocompatibility antigen, class I, HLA60, HLAG, HLAG_HUMAN, Major histocompatibility complex class I G, MHC class I antigen, MHC class I antigen G, MHC G, T-cell A locus, TCA
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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