Anti-HLA Class 1 ABC Antibody [Bra-23/9] - BSA and Azide free (A316468)

$765

Mouse monoclonal [Bra-23/9] antibody to HLA Class 1 ABC for Flow Cytometry and IF.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-HLA Class 1 ABC Antibody [Bra-23/9] - BSA and Azide free
Description
Mouse monoclonal [Bra-23/9] antibody to HLA Class 1 ABC.
Specificity
Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Immunoprecipitation of lactoperoxidase radioiodinated cell surface proteins and surface sialoglycoproteins radiolabeled by sodium metaperiodate/tritiated sodium borohydride technique confirmed the structure gp44,p12 (consisting of a 44kDa glycopeptide linked with a non-glycosylated 12kDa peptide) typical for MHC class I antigen(s) as a structure recognized by Bra23/9. Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
Applications
Flow Cytometry, IF
Positive Control
THP-1 and Jurkat cells. Tonsil or lymph node.
Dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivity
Human, Mouse, Non-Human Primates
Immunogen
Human REH cells (pre-B leukaemia cell line).
Host
Mouse
Clonality
Monoclonal
Clone ID
Bra-23/9
Isotype
IgG2a
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
~41 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
HLA A, HLA B, HLA C, HLA class 1 A, HLA class 1 B, HLA class 1 C, Major histocompatibility complex, class I, A + B + C, MHC class I HLA A, MHC class I HLA B, MHC class I HLA C, MHC HLA ABC
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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