Anti-HGF Antibody [EGH2 4C12.1] (A248821)

Anti-HGF Antibody [EGH2 4C12.1]

Mouse monoclonal [EGH2 4C12.1] antibody to HGF.

This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss.

Human

Recombinant full-length human HGF protein.

Mouse

Monoclonal

EGH2 4C12.1

IgG2b

kappa

Unconjugated

200 µg/ml

91 kDa / 64 kDa / 34 kDa precursor

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-HGF Antibody [EGH2 4C12.1] - BSA and Azide free (A252001).

DFNB39, F TCF, Fibroblast derived tumor cytotoxic factor, Hepatocyte growth factor, Hepatocyte growth factor (hepapoietin A; scatter factor), Hepatocyte growth factor beta chain, Hepatocyte growth factor precursor, Hepatopoietin A, Hepatopoietin-A, HGFB, HGF_HUMAN, HPTA, Lung fibroblast derived mitogen , OTTHUMP00000161349, OTTHUMP00000206710, OTTHUMP00000206711, OTTHUMP00000206712, OTTHUMP00000206713, OTTHUMP00000206730, Scatter factor, SF