Anti-GP2 Antibody [GP2/3133R] - BSA and Azide free
Description
Recombinant rabbit monoclonal [GP2/3133R] antibody to GP2.
Specificity
GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
Applications
ELISA
Positive Control
PANC-1 Cells. Pancreas
Dilutions
ELISA: 2-4 µg/ml for coating
Reactivity
Human
Immunogen
Recombinant fragment of human GP2 protein (around Amino Acids 35-179). The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
GP2/3133R
Isotype
IgG
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
59 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
GCTM-2 antigen, Gp200, MGC138240, PC, PCLP, PCLP-1, PCLP1, Pcx, Podocalyxin, Podocalyxin like, Podocalyxin like protein, Podocalyxin-like protein 1, PODXL, PODXL_HUMAN
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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