Anti-ZC3H7A Anticorps [PCRP-ZC3H7A-1D6] (A278224)

Name: Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] - BSA and Azide free
Brand: Antibodies.com
SKU: A278224
Price: 525.0 USD
Availability: InStock

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$525

Anticorps monoclonal [PCRP-ZC3H7A-1D6] de souris contre ZC3H7A pour ELISA, IP, Flow Cytometry et IF.

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Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Livraison

Frais de livraison

$40

Date de livraison

Livraison sous 4-6 jours ouvrables.

Nous ContacterContact

Téléphone

+1 (314) 370-6046

E-mail

orders@antibodies.com

Garanties

Qualité 100 % Garantie

Garantie de Correspondance des Prix

Mots clés :

Anticorps Monospécifique

Spécifications

Nom du produit

Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] - BSA and Azide free

Description du produit

Mouse monoclonal [PCRP-ZC3H7A-1D6] antibody to ZC3H7A.

Spécificité

The zinc finger CCCH domain-containing protein 7A (ZC3H7A), also known as ZC3H7, HSPC055 or ZC3HDC7, is a 971 amino acid protein that contains a C3H1-type zinc finger domain, three C3H1-type zinc fingers and three TPR repeats. Belonging to the ZC3H12 family, ZC3H7A localizes to the nucleus. Existing as two alternatively spliced isoforms, ZC3H7A is encoded by a gene located on human chromosome 16p13.13. Chromosome 16 makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of RubinsteinTaybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn s disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.

Applications

ELISA, IP, Flow Cytometry, IF

Recommander des dilutions

IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Reactivité

Human

Immunogène

Recombinant full-length human ZC3H7A protein.

Hôte

Mouse

Clonalité

Monoclonal

Clone

PCRP-ZC3H7A-1D6

Isotype

IgG1

Conjuguer

Unconjugated

Purification

Protein A/G chromatography.

Concentration

1 mg/ml

Masse moléculaire

110 kDa

Forme du produit

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Stockage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Notes générales

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] (A277636).

Synonymes

HSPC055, ZC3H7, ZC3HDC7, Zinc finger CCCH domain containing protein 7A, zinc finger CCCH type containing 7, zinc finger CCCH type containing 7A, zinc finger CCCH type domain containing 7, zinc finger protein AY163807

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Images (4)

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Figure 1: Flow Cytometry - Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] - BSA and Azide free (A278224)

Flow cytometric analysis of PFA-fixed HeLa cells using Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] followed by Goat Anti-Mouse IgG (CF® 488) (Blue). Isotype Control (Red).

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Figure 2: SDS-PAGE - Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] - BSA and Azide free (A278224)

SDS-PAGE analysis of Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.

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Figure 3: Immunofluorescence - Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] - BSA and Azide free (A278224)

Immunofluorescent analysis of PFA-fixed HeLa cells stained with Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] followed by Goat Anti-Mouse IgG (CF® 488) (Green). CF® 640A Phalloidin (Red).

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Figure 4: Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6] - BSA and Azide free (A278224)

Analysis of protein array containing more than 19,000 full-length human proteins using Anti-ZC3H7A Antibody [PCRP-ZC3H7A-1D6]. Z-Score and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt^TM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt^TM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target; a MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.