This antibody recognises human X-chromosome linked inhibitor of apoptosis (XIAP). XIAP is an endogenous inhibitor of cell death, which functions by suppressing caspases 3, 7, and 9. The protein is also reported to play a a role in the activation of NF kappa B and the regulation of cyclins and cyclin-dependent kinase inhibitors (CDKIs). Regulators of XIAP activity include XAF-1 and Smac. Rabbit anti Human XIAP antibody detects a band of approximately 57 kDa in human kidney lysates.

Applications

WB, IHC-P

Recommander des dilutions

IHC-P 1: 2 µg/ml, WB: 0.5 µg/ml - 2 µg/ml

Reactivité

Human, Mouse

Immunogène

Synthetic peptide corresponding to 13 amino acids within the C-terminus of human XIAP.

Hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Conjuguer

Unconjugated

Concentration

1 mg/ml

Forme du produit

Liquid

Formulation

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Stockage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Notes générales

Rabbit anti Human XIAP antibody recognizes human X-chromosome linked inhibitor of apoptosis (XIAP). XIAP is an endogenous inhibitor of cell death, which functions by suppressing caspases 3, 7, and 9. The protein is also reported to play a a role in the activation of NF kappa B and the regulation of cyclins and cyclin-dependent kinase inhibitors (CDKIs).Regulators of XIAP activity include XAF-1 and Smac. Rabbit anti Human XIAP antibody detects a band of approximately 57 kDa in human kidney lysates.

Synonymes

AP 13, API3, Apoptosis Inhibitor 3, Baculoviral IAP repeat containing 4, Baculoviral IAP Repeat Containing Protein 4, Baculoviral IAP repeat-containing protein 4, BIRC 4, BIRC4, E3 ubiquitin-protein ligase XIAP, hIAP-3, hIAP3, HILP, IAP 3, IAP like protein, IAP-3, IAP-like protein, IAP3, ILP, ILP 1, ILP1, Inhibitor of apoptosis protein 3, Inhibitor of Apoptosis X Linked, Mammalian IAP Homologue A, MIHA, X linked IAP, X linked inhibitor of apoptosis, X linked inhibitor of apoptosis E3 ubiquitin protein ligase, X linked inhibitor of apoptosis protein, X-linked IAP, X-linked inhibitor of apoptosis protein, XIAP_HUMAN, XLP2

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.