Anti-VEGF Receptor 2 Anticorps [DC101] (A250834)

Anticorps monoclonal [DC101] de rat contre VEGF Receptor 2 pour WB et Neutralization Studies.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-VEGF Receptor 2 Antibody [DC101]
Description du produit
Rat monoclonal [DC101] antibody to VEGF Receptor 2.
Spécificité
This antibody is specific to Mouse VEGFR2/FLK-1/CD309 and does not cross-react with FLK-2. VEGFR2 is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Endothelial cells, embryonic tissues, and megakaryocytes mainly express VEGFR2. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.
Applications
WB, Neutralization Studies
Recommander des dilutions
WB (non-reducing): 2-5 µg/ml
Reactivité
Mouse
Immunogène
Recombinant full-length mouse VEGFR2 protein.
Hôte
Rat
Clonalité
Monoclonal
Clone
DC101
Isotype
IgG1
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
180-190 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales

This antibody blocks binding of VEGF to VEGF-R2, inhibits VEGF-induced signaling, and blocks tumor growth in mice; order antibody without BSA and Sodium Azide!

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-VEGF Receptor 2 Antibody [DC101] - BSA and Azide free (A254014).

Synonymes
CD309, CD309 antigen, EC 2.7.10.1, Fetal liver kinase 1, FLK-1, FLK1, FLK1, mouse, homolog of, Kdr, Kinase insert domain receptor, Kinase insert domain receptor (a type III receptor tyrosine kinase), KRD1, Ly73, Protein tyrosine kinase receptor FLK1, Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, Tyrosine kinase growth factor receptor, Vascular endothelial growth factor receptor 2, VEGFR, VEGFR 2, VEGFR-2, VEGFR2, VGFR2_HUMAN
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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