Anti-UACA Anticorps [UACA/1222] (A252873)

Anti-UACA Antibody [UACA/1222] - BSA and Azide free

Mouse monoclonal [UACA/1222] antibody to UACA.

UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

WB

WB: 1-2 µg/ml

Human, Mouse

Recombinant human UACA protein.

Mouse

Monoclonal

UACA/1222

IgG1

kappa

Protein A/G chromatography.

1 mg/ml

160 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-UACA Antibody [UACA/1222] (A249693).

FLJ10128, KIAA1561, MGC141967, MGC141969, Nuclear membrane binding protein, NUCLING, UACA_HUMAN, Uveal autoantigen with coiled coil domains and ankyrin repeats, Uveal autoantigen with coiled-coil domains and ankyrin repeats