Recombinant Anti-TRPS1 Anticorps [TRPS1/7912R] (A315763)

Anti-TRPS1 Antibody [TRPS1/7912R]

Recombinant rabbit monoclonal [TRPS1/7912R] antibody to TRPS1.

Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes. Ubiquitously expressed in the adult. Found in fetal brain, lung, kidney, liver, spleen and thymus. More highly expressed in androgen-dependent than in androgen-independent prostate cancer cells.

IHC-P

Human squamous epithelium, breast or breast cancer.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 900-1100) of human TRPS1 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

TRPS1/7912R

IgG

Unconjugated

Protein A/G chromatography.

200 µg/ml

142 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

GC79, LGCR, Transcriptional repressor GATA binding 1, Tricho rhino phalangeal syndrome I, Tricho-rhino-phalangeal syndrome type I protein, Trichorhinophalangeal syndrome I, Trichorhinophalangeal syndrome I homolog, TRPS 1, TRPS1 gene, TRPS1_HUMAN, Zinc finger protein GC79, Zinc finger transcription factor TRPS 1, Zinc finger transcription factor Trps1