Anti-TRP1 Anticorps [TYRP1/8313R] (A315759)

$765

Anticorps monoclonal [TYRP1/8313R] de lapin contre TRP1 pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-TRP1 Antibody [TYRP1/8313R]
Description du produit
Rabbit monoclonal [TYRP1/8313R] antibody to TRP1.
Spécificité
It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Applications
IHC-P
Contrôle positif
SK-MEL-23, SK-MEL-19, SK-MEL-30 or SK-MEL-37 cells. Human melanoma.
Recommander des dilutions
IHC: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment (around Amino Acids 200-400) of human TYRP1 protein. The exact sequence is proprietary.
Hôte
Rabbit
Clonalité
Monoclonal
Clone
TYRP1/8313R
Isotype
IgG
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A chromatography.
Concentration
200 µg/ml
Masse moléculaire
75 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonymes
5, 5,6 dihydroxyindole 2 carboxylic acid oxidase, 6-dihydroxyindole-2-carboxylic acid oxidase, b-PROTEIN, CAS2, Catalase B, CATB, DHICA oxidase, Glycoprotein 75, GP75, Melanoma antigen gp75, OCA3, TRP, TRP-1, Tyrosinase related protein 1, Tyrosinase-related protein 1, TYRP, TYRP1, TYRP1_HUMAN, TYRRP
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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