Anti-Transferrin Anticorps [TF/4796] (A317130)

$765

Anticorps monoclonal [TF/4796] de souris contre Transferrin pour ELISA et IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-Transferrin Antibody [TF/4796] - BSA and Azide free
Description du produit
Mouse monoclonal [TF/4796] antibody to Transferrin.
Spécificité
Iron (Fe) is a tightly metabolically controlled mineral and growth factor present in all living cells. Iron not bound in erythrocyte hemoglobin is transported by transferrin (Tf), the iron transport protein of vertebrate serum. The transferrin protein contains two homologous domains, each of which contain an Fe-binding site. The majority of transferrin is synthesized in the liver and secreted into the blood, but it is also produced in lower amounts in testis and brain as well as in oligodendrocytes, where transferrin is an early marker of oligodendrocyte differentiation. From the blood, transferrin is internalized by erythroblasts and reticulocytes upon binding the transferrin receptor (TfR), also designated CD71, through a system of coated pits and vesicles. After Fe release, transferrin is returned to the extracellular medium, where it can be reused. Defects in the transferrin gene results in atransferrinemia, a rare autosomal recessive disorder characterized by microcytic anemia and iron loading.
Applications
ELISA, IHC-P
Contrôle positif
Human liver or hepatocellular carcinoma.
Recommander des dilutions
ELISA: 2-4 µg/ml for coating, IHC: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment (around Amino Acids 311-445) of human TF protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
TF/4796
Isotype
IgG2
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
79 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonymes
Apotransferrin, ATRAF, Atransferrinemia, Beta 1 metal binding globulin, Beta-1 metal-binding globulin, DKFZp781D0156, HEL S 71p, HELS71p, PRO1400, PRO1557, PRO2086, Serotransferrin, Serotransferrin precursor, Siderophilin, TF, TFQTL1, Transferin, TRFE_HUMAN
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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