Recombinant Anti-TOP1MT Anticorps [rTOP1MT/488] (A278468)

Name: Anti-TOP1MT Antibody [rTOP1MT/488] - BSA and Azide free
Brand: Antibodies.com
SKU: A278468
Price: 525.0 USD
Availability: InStock

Cliquez pour ouvrir le point de vue élargi

$525

Anticorps monoclonal [rTOP1MT/488] de souris contre TOP1MT pour Flow Cytometry, IF, WB et IHC-P.

Qualité 100 % Garantie

Garantie de Correspondance des Prix

Alternative Formats and ConjugatesAlternative Formats

Unconjugated

Livraison

Frais de livraison

$40

Date de livraison

Livraison sous 4-6 jours ouvrables.

Nous ContacterContact

Téléphone

+1 (314) 370-6046

E-mail

orders@antibodies.com

Garanties

Qualité 100 % Garantie

Garantie de Correspondance des Prix

Mots clés :

Anticorps Recombinant

Spécifications

Nom du produit

Anti-TOP1MT Antibody [rTOP1MT/488] - BSA and Azide free

Description du produit

Recombinant mouse monoclonal [rTOP1MT/488] antibody to TOP1MT.

Spécificité

DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Applications

Flow Cytometry, IF, WB, IHC-P

Recommander des dilutions

Flow Cytometry: 0.5-1 µg/million cells, IF: 0.5-1 µg/ml, WB: 0.5-2 µg/ml, IHC-P: 1-2 µg/ml

Reactivité

Human

Immunogène

Recombinant full-length human TOP1MT protein.

Hôte

Mouse

Clonalité

Monoclonal

Clone

rTOP1MT/488

Isotype

IgG1

Chaînes légères

kappa

Conjuguer

Unconjugated

Purification

Protein A/G chromatography.

Concentration

1 mg/ml

Masse moléculaire

70 kDa

Forme du produit

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Stockage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Notes générales

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-TOP1MT Antibody [rTOP1MT/488] (A277880).

Synonymes

2900052H09Rik, DNA topoisomerase I, DNA topoisomerase I, mitochondrial, mitochondrial, TOP1M_HUMAN, Topoisomerase I mitochondrial

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Images (2)

Cliquez pour ouvrir le point de vue élargi

Figure 1: Immunohistochemistry - Anti-TOP1MT Antibody [rTOP1MT/488] - BSA and Azide free (A278468)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human liver tissue using Anti-TOP1MT Antibody [rTOP1MT/488].

Cliquez pour ouvrir le point de vue élargi

Figure 2: SDS-PAGE - Anti-TOP1MT Antibody [rTOP1MT/488] - BSA and Azide free (A278468)

SDS-PAGE analysis of Anti-TOP1MT Antibody [rTOP1MT/488] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.