Anti-Thyroglobulin Anticorps [TGB04 + TGB05] (A253288)

Anticorps Oligoclonal [TGB04 + TGB05] de souris contre Thyroglobulin pour Flow Cytometry et IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-Thyroglobulin Antibody [TGB04 + TGB05] - BSA and Azide free
Description du produit
Mouse monoclonal [TGB04 + TGB05] antibody to Thyroglobulin.
Spécificité
Thyroglobulin is a 660kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
Applications
Flow Cytometry, IHC-P
Recommander des dilutions
Flow Cytometry: 0.5-1 µg/million cells, IHC-P: 1-2 µg/ml
Reactivité
Human, Mouse, Rat
Immunogène
Human thyroid follicular cells.
Hôte
Mouse
Clonalité
Oligoclonal
Clone
TGB04 + TGB05
Isotype
IgG1, kappa + IgG1, kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
660 kDa (dimeric Form)
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales

Please note, this product is an oligoclonal antibody; it is a cocktail of monoclonal antibodies that have been carefully selected. Oligoclonal antibodies not only have the specificity and batch-to-batch consistency of a monoclonal antibody, but they also have the advantage of the sensitivity of a polyclonal antibody due to their ability to recognize multiple epitopes on an antigen.

This oligoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Thyroglobulin Antibody [TGB04 + TGB05] (A250108).

Synonymes
AITD 3, AITD3, hTG, TDH3, Tg, TGN, THYG_HUMAN
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Produits alternatifs à Anti-Thyroglobulin Anticorps [TGB04 + TGB05] (A253288)

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