Anti-Thymidylate Synthase Anticorps [TS106] (A281843)

Anti-Thymidylate Synthase Antibody [TS106]

Mouse monoclonal [TS106] antibody to Thymidylate Synthase.

This antibody recognises thymidylate synthase, an enzyme that is essential for DNA biosynthesis and acts by converting dUMP to dTMP.Thymidylate synthase is a target for the fluoropyrimidine group of cytotoxic drugs that are used to treat solid tumours.

WB, IHC-P, IF, IP, Flow Cytometry, IHC-Fr, ELISA

IHC-Fr: 1:50 - 1:100, IHC-P: 1:50 - 1:100, WB: 1:200 - 1:400

Human

Recombinant thymidylate synthase.

Mouse

Monoclonal

TS106

IgG1

Unconjugated

Protein A affinity chromatography of tissue culture supernatant.

Approximately 36 kDa under reduced conditions.

Liquid

Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human thymidylate synthase antibody, clone TS106 recognizes thymidylate synthase, an enzyme that is essential for DNA biosynthesis and acts by converting dUMP to dTMP.Thymidylate synthase is a target for the fluoropyrimidine group of cytotoxic drugs that are used to treat solid tumours.

d TMP synthase, EC 2.1.1.45, HsT422, MGC88736, OTTHUMP00000162195, Thymidylate synthetase, TMS, TS, TSase, Tyms, TYMS protein, Tyms thymidylate synthetase, TYSY_HUMAN