Mouse monoclonal [TGFA/1119] antibody to TGF alpha.
Spécificité
This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Applications
IHC-P
Recommander des dilutions
IHC-P: 2-4 µg/ml
Reactivité
Human
Immunogène
Recombinant full-length human TGF alpha protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
TGFA/1119
Isotype
IgG1
Chaînes légères
kappa
Conjuguer
Unconjugated
Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
~6 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.