Recombinant Anti-STING Anticorps [STING1/8187R] (A315686)

Anti-STING Antibody [STING1/8187R]

Recombinant rabbit monoclonal [STING1/8187R] antibody to STING.

TMEM17 (transmembrane protein 173) is a 379 amino acid protein encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

IHC-P

Cytoplasmic expression in several tissues including cells in respiratory tract, fallopian tube and cells in lymphoid tissues.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 190-290) of human TMEM173 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

STING1/8187R

kappa

Unconjugated

Protein A/G chromatography.

200 µg/ml

37-50 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

endoplasmic reticulum IFN stimulator, Endoplasmic reticulum interferon stimulator, ERIS, FLJ38577, hMITA, hSTING, Mediator of IRF3 activation, MITA, Mitochondrial mediator of IRF3 activation, MPYS, N terminal methionine proline tyrosine serine plasma membrane tetraspanner, NET23, Stimulator of interferon genes, Stimulator of interferon genes protein, TM173_HUMAN, TMEM173, Transmembrane protein 173