Anti-Spastin Anticorps [Sp 3G11-1] (A253201)

Anticorps monoclonal [Sp 3G11-1] de souris contre Spastin pour ELISA, IF, WB et IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-Spastin Antibody [Sp 3G11-1] - BSA and Azide free
Description du produit
Mouse monoclonal [Sp 3G11-1] antibody to Spastin.
Spécificité
The AAA protein family members share an ATPase domain and have roles in various cellular processes including intracellular motility, membrane trafficking, proteolysis, protein folding and organelle biogenesis. Spastin, a member of the AAA protein family, is a 616 amino acid protein and is involved in the function or assembly of nuclear protein complexes. The Spastin protein is expressed ubiquitously and localizes to the nucleus and the cytoplasm, where it may also be involved in microtubule dynamics. Mutations in the Spastin gene (SPAST, SPG4) cause the most common form of spastic paraplegia 4, an autosomal dominant form of hereditary spastic paraplegia (HSP). HSPs comprise a group of inherited neurological disorders characterized by spastic lower extremity weakness due to a length-dependent, retrograde axonopathy of corticospinal motor neurons. SPAST-specific mutations account for approximately 40% of all autosomal dominant HSPs.
Applications
ELISA, IF, WB, IHC-P
Recommander des dilutions
IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivité
Human, Mouse, Rat
Immunogène
Recombinant full-length human Spastin protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
Sp 3G11-1
Isotype
IgG2a
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
52 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Spastin Antibody [Sp 3G11-1] (A250021).
Synonymes
ADPSP, FSP 2, FSP2, KIAA1083, Spast, Spastic paraplegia 4, spastic paraplegia 4 (autosomal dominant; spastin), SPG 4, SPG4, SPG4 gene
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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