This antibody recognises the human pre-synaptic protein, SNAP-25, also known as Synaptosomal-associated protein 25, Super protein (SUP) or Synaptosomal-associated 25 kDa protein. SNAP-25 is a 206 amino acid presynaptic protein of ~25 kDa containing two t-SNARE coiled-coil homology domains. Mouse anti human SNAP-25 antibody, clone SP12 will recognize SNAP-25 fusion protein from COS cells, but not the fusion protein from bacterial systems. Mouse anti Human SNAP-25 antibody, clone SP12 has been used to study the distribution of synaptic changes in the hippocampus of patients with medically refractory temporal lobe epilepsy.

Applications

WB, IHC-P, ELISA

Recommander des dilutions

IHC-P: 1:2,000 - 1:5,000, WB: 1:500 - 1:5,000

Reactivité

Human, Hamster, Pig, Rat, Gerbil

Immunogène

Crude human synaptic immunoprecipitate.

Hôte

Mouse

Clonalité

Monoclonal

Clone

SP12

Isotype

IgG1

Conjuguer

Unconjugated

Purification

Protein A affinity chromatography of tissue culture supernatant.

Concentration

1 mg/ml

Forme du produit

Liquid

Formulation

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Stockage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Notes générales

Mouse anti Human SNAP-25 antibody, clone SP12 recognizes the human pre-synaptic protein, SNAP-25, also known as Synaptosomal-associated protein 25, Super protein (SUP) or Synaptosomal-associated 25 kDa protein. SNAP-25 is a 206 amino acid presynaptic protein of ~25 kDa containing two t-SNARE coiled-coil homology domains. Mouse anti human SNAP-25 antibody, clone SP12 will recognize SNAP-25 fusion protein from COS cells, but not the fusion protein from bacterial systems.Mouse anti Human SNAP-25 antibody, clone SP12 has been used to study the distribution of synaptic changes in the hippocampus of patients with medically refractory temporal lobe epilepsy. (Honer et al. 1994).

Synonymes

bA416N4.2, Bdr, CMS18, dJ1068F16.2, FLJ23079, HGNC:11132, MGC105414, MGC139754, Resistance to inhibitors of cholinesterase 4 homolog, RIC 4, RIC4, SEC 9, SEC9, SNAP, SNAP 25, SNAP-25, SNAP-25B, SNP 25, SNP25, SNP25_HUMAN, sp, SUP, Super protein, Synaptosomal associated 25 kDa protein, Synaptosomal associated protein, Synaptosomal associated protein 25, Synaptosomal associated protein 25kDa, Synaptosomal-associated 25 kDa protein, Synaptosomal-associated protein 25, Synaptosomal-associated protein, 25-KD

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.