This antibody recognises the serotonin transporter, also known as Sodium-dependent serotonin transporter, 5HT transporter or Solute carrier family 6 member 4. Serotonin transporter is a 630 amino acid ~70 kDa multiple pass endosomal membrane protein. Serotonin transporter is involved in the transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization and in regulating availability of serotonin to receptors of the serotonergic system.

Applications

IHC-Fr

Recommander des dilutions

IHC-Fr: 0.5 µg/ml - 1 µg/ml

Reactivité

Rat, Mouse

Immunogène

Rat serotonin transporter, N-terminus/GST fusion protein corresponding to amino acids 1-85.

Hôte

Mouse

Clonalité

Monoclonal

Clone

2D7/3

Isotype

IgG1

Conjuguer

Unconjugated

Purification

Protein G affinity chromatography of ascites.

Concentration

1 mg/ml

Forme du produit

Liquid

Formulation

Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.

Stockage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Notes générales

Mouse anti Rat serotonin transporter antibody, clone 2D7/3 reacts with the serotonin transporter, also known as Sodium-dependent serotonin transporter, 5HT transporter or Solute carrier family 6 member 4. Serotonin transporter is a 630 amino acid ~70 kDa multiple pass endosomal membrane protein. Serotonin transporter is involved in the transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization and in regulating availability of serotonin to receptors of the serotonergic system.

Synonymes

5 HTT, 5 HTTLPR, 5 hydroxytryptamine (serotonin) transporter, 5 hydroxytryptamine transporter, 5HT transporter, 5HTT, hSERT, HTT, Na+/Cl- dependent serotonin transporter, OCD1, SC6A4_HUMAN, Serotonin transporter 1, SERT, SERT1, Slc6a4, Sodium dependent serotonin transporter, Sodium-dependent serotonin transporter, Solute carrier family 6 (neurotransmitter transporter) member 4, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, Solute carrier family 6 member 4

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.