Anti-Semaphorin 4D Antibody [SEMA4D/933] (A248146)

Anti-Semaphorin 4D Antibody [SEMA4D/933]

Mouse monoclonal [SEMA4D/933] antibody to Semaphorin 4D.

This antibody recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

Flow Cytometry, IF

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Human, Non-Human Primates

Recombinant human SEMA4D protein.

Mouse

Monoclonal

SEMA4D/933

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

50 kDa (monomer)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Semaphorin 4D Antibody [SEMA4D/933] - BSA and Azide free (A251329).