Recombinant Anti-SDHB Anticorps [rSDHB/6948] (A315633)

$765

Anticorps monoclonal [rSDHB/6948] de souris contre SDHB pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-SDHB Antibody [rSDHB/6948]
Description du produit
Recombinant mouse monoclonal [rSDHB/6948] antibody to SDHB.
Spécificité
Succinate dehydrogenase B (SDHB) is an iron-sulfur subunit of mitochondrial complex II, a key component of the citric acid cycle and the electron transport chain, a respiratory complex that catalyzes the oxidation of succinate in the mitochondrial membrane.Many cancers are generally positive for SDHB, including renal cell carcinomas and gastrointestinal stromal tumors. A subset of RCC and GIST tumors that are associated with SDH mutations, Carney-Stratakis Syndrome or Carney Triad exhibit a loss of SDHB expression.
Applications
IHC-P
Contrôle positif
Jurkat or HepG2 cells. Human kidney or heart tissue.
Recommander des dilutions
IHC: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment (around Amino Acids 180-280) of human SDHB protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
rSDHB/6948
Isotype
IgG1
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
32 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonymes
CWS2, DHSB_HUMAN, FLJ92337, Ip, Iron sulfur subunit, Iron sulfur subunit of complex II, Iron-sulfur subunit of complex II, mitochondrial, PGL 4, PGL4, SDH, SDH 1, SDH1, SDH2, SDH2, homolog of, SDHIP, Succinate Dehydrogenase 1 Iron Sulfur Subunit, Succinate Dehydrogenase 2, S. cerevisiae, homolog of, Succinate dehydrogenase complex iron sulfur subunit B, Succinate dehydrogenase complex subunit B iron sulfur, Succinate Dehydrogenase Complex Subunit B Iron Sulfur Protein, succinate dehydrogenase complex, subunit B, iron sulfur (Ip), Succinate dehydrogenase iron sulfur protein, Succinate dehydrogenase [ubiquinone] iron sulfur protein mitochondrial, Succinate dehydrogenase [ubiquinone] iron sulfur subunit, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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