Recombinant Anti-Sarcomeric alpha Actinin Anticorps [rACTN2/7361] (A315604)

$765

Anticorps monoclonal [rACTN2/7361] de souris contre Sarcomeric alpha Actinin pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-Sarcomeric alpha Actinin Antibody [rACTN2/7361]
Description du produit
Recombinant mouse monoclonal [rACTN2/7361] antibody to Sarcomeric alpha Actinin.
Spécificité
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
Applications
IHC-P
Contrôle positif
Human skeletal or cardiac muscle.
Recommander des dilutions
IHC: 1-2 µg/ml
Reactivité
Human
Immunogène
A recombinant fragment (aa557-692) of human ACTN2 protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
rACTN2/7361
Isotype
IgG1
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
103 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonymes
Actin binding protein, Actinin alpha 2, ACTN 2, ACTN2, ACTN2_HUMAN, Alpha actinin 2, Alpha actinin skeletal muscle, Alpha actinin skeletal muscle isoform 2, Alpha-actinin skeletal muscle isoform 2, Alpha-actinin-2, CMD1AA, F actin cross linking protein, F-actin cross-linking protein
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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