This antibody recognises rotavirus and is specific for ICPs and late structural (virion) antigens. It has been reported to exhibit 90% cross reactivity with human rotavirus and does not react with HEp-2 cells or WI-38 cells in immunofluorescence.Rotavirus is a virus that infects the bowels and is the most common cause of gastroenteritis in infants. 7 major groups have currently been identified, 3 of which infect humans (groups A, B and C). The rotavirus genome consists of 11 segments of double stranded RNA held in the inner core of the three layered, icosahedral virion particle. The genome codes for 6 virus proteins (VP1,2,3,4,6,7) and 6 non-structural proteins (NSP1-6). Outer capsid proteins are VP4 and VP7, inner capsid -VP6 and core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection; therefore, multiple serotypes of rotavirus mean multiple opportunities for infection.

Applications

Reactivité

Viral

Immunogène

Nebraska calf diarrhea virus.

Hôte

Goat

Clonalité

Polyclonal

Isotype

IgG

Conjuguer

Unconjugated

Concentration

5 mg/ml

Forme du produit

Liquid

Formulation

Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.

Stockage

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Notes générales

Goat anti Rotavirus antibody reacts with rotavirus and is specific for ICPs and late structural (virion) antigens. It has been reported to exhibit 90% cross reactivity with human rotavirus and does not react with HEp-2 cells or WI-38 cells in immunofluorescence.Rotavirus is a virus that infects the bowels and is the most common cause of gastroenteritis in infants. 7 major groups have currently been identified, 3 of which infect humans (groups A, B and C). The rotavirus genome consists of 11 segments of double stranded RNA held in the inner core of the three layered, icosahedral virion particle. The genome codes for 6 virus proteins (VP1,2,3,4,6,7) and 6 non-structural proteins (NSP1-6). Outer capsid proteins are VP4 and VP7, inner capsid -VP6 and core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection; therefore, multiple serotypes of rotavirus mean multiple opportunities for infection.

Synonymes

Major inner capsid protein VP6, NSP4, VP6

Contrôles isotype