Recombinant Anti-RCAS1 Anticorps [rEBAG9/7264] (A316928)

$765

Anticorps monoclonal [rEBAG9/7264] de souris contre RCAS1 pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-RCAS1 Antibody [rEBAG9/7264] - BSA and Azide free
Description du produit
Recombinant mouse monoclonal [rEBAG9/7264] antibody to RCAS1.
Spécificité
EBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients.
Applications
IHC-P
Contrôle positif
MCF-7, Jurkat or HEK-293 cell lysates. Human skeletal muscle tissue.
Recommander des dilutions
IHC: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant full-length human EBAG9 protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
rEBAG9/7264
Isotype
IgG1
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
32 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonymes
BAG9, Cancer associated surface antigen, Cancer associated surface antigen RCAS1, Cancer-associated surface antigen RCAS1, EB9, EBAG 9, EBAG9, Estrogen receptor binding fragment associated gene 9 protein, Estrogen receptor binding site associated antigen 9, estrogen receptor binding site associated, antigen, 9, Estrogen receptor-binding fragment-associated gene 9 protein, PDAF, RCAS 1, RCAS1_HUMAN, Receptor binding cancer antigen expressed on SiSo cells, Receptor-binding cancer antigen expressed on SiSo cells
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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