Anti-RBP4 Anticorps [RBP4/4044] (A253030)

Anticorps monoclonal [RBP4/4044] de souris contre RBP4 pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-RBP4 Antibody [RBP4/4044] - BSA and Azide free
Description du produit
Mouse monoclonal [RBP4/4044] antibody to RBP4.
Spécificité
Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal Vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP, resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with Insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.
Applications
IHC-P
Recommander des dilutions
IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment, around amino acids 29-148, of human RBP4 protein. The exact sequence is proprietary.
Hôte
Mouse
Clonalité
Monoclonal
Clone
RBP4/4044
Isotype
IgG2b
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
25 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-RBP4 Antibody [RBP4/4044] (A249850).
Synonymes
OTTHUMP00000020114, OTTHUMP00000020115, OTTHUMP00000020116, Plasma retinol binding protein 4, Plasma retinol-binding protein, Plasma retinol-binding protein(1-176), PRBP, PRO2222, RBP, RDCCAS, RET4_HUMAN, Retinol binding protein 4, Retinol binding protein 4 interstitial, Retinol binding protein 4 plasma
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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