Anti-RAGE Anticorps [B02-4G7] (A279728)

$340

Anticorps monoclonal [B02-4G7] de souris contre RAGE pour ELISA.

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-RAGE Antibody [B02-4G7]
Description du produit
Mouse monoclonal [B02-4G7] antibody to RAGE.
Spécificité
This antibody recognises Receptor for Advanced Glycosylation End products (RAGE), also known as advanced glycosylation end product-specific receptor. RAGE is a multi-ligand receptor belonging to the immunoglobulin receptor subfamily. It has many endogenous and exogenous ligands and upon binding of a ligand, RAGE can stimulate various signaling pathways including NF-?B, AP-1, CREB and STAT3. Triggering these pathways can then induce cytokine/chemokine transcription. This can be used to regulate the innate immune response, inflammation resolution, tissue homeostasis and tissue repair following injury. The purified Mouse anti Human RAGE antibody, clone B02-4G7 (MCA62676GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human RAGE antibody, clone A09-5H8 (MCA6277B) as the detection antibody.
Applications
ELISA
Recommander des dilutions
ELISA: 1 µg/ml
Reactivité
Human
Immunogène
E. coli derived recombinant human full length RAGE (Ala23-Pro404).
Hôte
Mouse
Clonalité
Monoclonal
Clone
B02-4G7
Isotype
IgG1
Conjuguer

Unconjugated

Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Forme du produit
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Stockage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Notes générales
Mouse anti Human RAGE antibody, clone B02-4G7, recognizes Receptor for Advanced Glycosylation End products (RAGE), also known as advanced glycosylation end product-specific receptor. RAGE is a multi-ligand receptor belonging to the immunoglobulin receptor subfamily. It has many endogenous and exogenous ligands and upon binding of a ligand, RAGE can stimulate various signaling pathways including NF-?B, AP-1, CREB and STAT3. Triggering these pathways can then induce cytokine/chemokine transcription (Sorci et al. 2013). This can be used to regulate the innate immune response, inflammation resolution, tissue homeostasis and tissue repair following injury (Plotkin et al. 2019). The purified Mouse anti Human RAGE antibody, clone B02-4G7 (MCA62676GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human RAGE antibody, clone A09-5H8 (MCA6277B) as the detection antibody.
Synonymes
Advanced glycosylation end product-specific receptor, Ager, MGC2235, RAGE_HUMAN, Receptor for advanced glycosylation end products
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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