Anti-PU.1 Anticorps [PU1/2118] (A278397)

Anti-PU.1 Antibody [PU1/2118] - BSA and Azide free

Mouse monoclonal [PU1/2118] antibody to PU.1.

PU.1 is a member of the ETS family of transcription factors and is important for normal B-cell development. It is expressed in the myeloid lineage and in immature as well as mature B-lymphocytes, with the exception of plasma cells. PU.1 is expressed in germinal center B-cells and mantle B-cells. Various lymphomas are also positive for this marker. It is essential during early B-cell differentiation. The absence of PU.1 results in total block of B-cell development at the pre-pro stage. PU.1 plays a key role in normal myeloid differentiation, and regulates the expression of immunoglobulin and other genes that are important for B-cell development.

IHC-P

IHC-P: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 16-170, of human PU.1. The exact sequence is proprietary.

Mouse

Monoclonal

PU1/2118

IgG1

Unconjugated

1 mg/ml

40 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-PU.1 Antibody [PU1/2118] (A277809).

transcription factor spi1, 31 kDa Transforming Protein, 31 kDa-transforming protein, cb1086, Hematopoietic transcription factor PU.1, OF, oncogene spi1, PU.1/Spi1, SFFV virus-induced murine erythroleukemia oncogene, mouse, homolog of, SFPI1, si:by184l24.2, SPI 1, SPI 1 proto oncogene, SPI A, Spi1, SPI1_HUMAN, Spleen focus forming virus (SFFV) proviral integration oncogene spi1, Spleen focus forming virus proviral integration oncogene spi1, Transcription factor PU.1