Anti-Prostate Specific Antigen Anticorps [A67-B/E3 + 1A7] (A249007)

Anti-Prostate Specific Antigen Antibody [A67-B/E3 + 1A7]

Mouse monoclonal [A67-B/E3 + 1A7] antibody to Prostate Specific Antigen.

This antibody recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human

Native PSA from human sperm plasma.

Mouse

Oligoclonal

A67-B/E3 + 1A7

IgG1, kappa + IgG1, kappa

Protein A/G chromatography.

200 µg/ml

33-34 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

antigen, prostate-specific, APS, Gamma seminoprotein, Gamma-seminoprotein, hK3, Kallikrein 3, Kallikrein related peptidase 3, Kallikrein-3, KLK 3, KLK2A1, Klk3, KLK3_HUMAN, P-30 antigen, P30 antigen, Prostate-specific antigen, Psa, Semenogelase, Seminin