Neurotrophin 3 est un gène codé par le symbole NTF3. Communément appelé aussi: Neurotrophin-3; NT-3; HDNF; Nerve growth factor 2; NGF-2; Neurotrophic factor; NTF3. Neurotrophin 3 a une masse de 29.36kDa et une longueur d'acide aminé de 257.
Nous proposons 2 Neurotrophin 3 protéines
Informations sur les Gènes et les Protéines
Résumé UniProt
Seems to promote the survival of visceral and proprioceptive sensory neurons.
Résumé Entrez
The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
Spécificité tissulaire
Brain and peripheral tissues.
Similitudes de séquence
Belongs to the NGF-beta family.
Localisation cellulaire
Secreted.
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