Neuritin est un gène codé par le symbole NRN1. Communément appelé aussi: NRN1; NRN. Neuritin a une masse de 15.33kDa et une longueur d'acide aminé de 142.
Nous proposons 2 Neuritin protéines
Informations sur les Gènes et les Protéines
Résumé UniProt
Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells.
Résumé Entrez
This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants.
Similitudes de séquence
Belongs to the neuritin family.
Localisation cellulaire
Cell membrane. Cell junction > Synapse.
Liens de base de données
