CXCL5 est un gène codé par le symbole CXCL5. D'autres noms incluent: C-X-C motif chemokine 5; ENA-78(1-78); Epithelial-derived neutrophil-activating protein 78; Neutrophil-activating peptide ENA-78; Small-inducible cytokine B5; ENA78; SCYB5. CXCL5 a une masse de 11.97kDa et une longueur d'acide aminé de 114.
Nous proposons 7 CXCL5 protéines
Informations sur les Gènes et les Protéines
Résumé UniProt
Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes.
Résumé Entrez
This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion.
Similitudes de séquence
Belongs to the intercrine alpha (chemokine CxC) family.
Modification post-traductionnelle
N-terminal processed forms ENA-78(8-78) and ENA-78(9-78) are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Localisation cellulaire
Secreted.
Liens de base de données
