CXCL16 est un gène codé par le symbole CXCL16. D'autres noms incluent: C-X-C motif chemokine 16; Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SR-PSOX; Small-inducible cytokine B16; Transmembrane chemokine SCYB16; SRPSOX. CXCL16 a une masse de 27.58kDa et une longueur d'acide aminé de 254.
Nous proposons 3 CXCL16 protéines
Informations sur les Gènes et les Protéines
Résumé UniProt
Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
Spécificité tissulaire
Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
Similitudes de séquence
Belongs to the intercrine alpha (chemokine CxC) family.
Modification post-traductionnelle
Glycosylated.
Localisation cellulaire
Cell membrane. Secreted.
Also exists as a soluble form.
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