CD80 est un gène codé par le symbole CD80. D'autres noms incluent: T-lymphocyte activation antigen Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD28LG; CD28LG1; LAB7. CD80 a une masse de 33.05kDa et une longueur d'acide aminé de 288.
Nous proposons 6 CD80 protéines
Informations sur les Gènes et les Protéines
Résumé UniProt
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.
Résumé Entrez
The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
Spécificité tissulaire
Expressed on activated B-cells, macrophages and dendritic cells.
Localisation cellulaire
Membrane.
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