Apolipoprotein D est un gène codé par le symbole APOD. D'autres noms incluent: Apo-D; APOD. Apolipoprotein D a une masse de 21.28kDa et une longueur d'acide aminé de 189.
Nous proposons 3 Apolipoprotein D protéines
Informations sur les Gènes et les Protéines
Résumé UniProt
APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.
Résumé Entrez
This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism.
Spécificité tissulaire
Expressed in liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears.
Similitudes de séquence
Belongs to the calycin superfamily. Lipocalin family.
Modification post-traductionnelle
N-glycosylatd. N-glycan heterogeneity at Asn-65: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor); at Asn-98: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major), dHex1Hex6HexNAc5 (minor) and dHex1Hex7HexNAc6 (minor).
Localisation cellulaire
Secreted.
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