Vitronectin est un gène codé par le symbole VTN. Il est également connu sous le nom de: VN; S-protein; Serum-spreading factor; V75; VTN. Vitronectin a une masse de 54.31kDa et une longueur d'acide aminé de 478.
Nous proposons 7 des anticorps contre Vitronectin, élevé dans Lapin et Souris, qui sont appropriés pour le WB, IHC, ELISA et ICC/IF avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.
Résumé Entrez
The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
Spécificité tissulaire
Expressed in the retina pigment epithelium (at protein level) (PubMed:25136834). Plasma.
Modification post-traductionnelle
Sulfated on tyrosine residues.
Localisation cellulaire
Secreted > Extracellular space.
