RAP2C est un gène codé par le symbole RAP2C. Il est également connu sous le nom de Ras-related protein Rap-2c. RAP2C a une masse de 20.75kDa et une longueur d'acide aminé de 183.
Nous proposons 3 des anticorps contre RAP2C, élevé dans Lapin, qui sont appropriés pour le WB, IHC et ELISA avec des échantillons dérivés de Humain et Souris.
Informations sur les Gènes et les Protéines
Résumé UniProt
Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription.
Résumé Entrez
The protein encoded by this gene is a member of the Ras-related protein subfamily of the Ras GTPase superfamily. Members of this family are small GTPases that act as molecular switches to regulate cellular proliferation, differentiation, and apoptosis. This protein has been reported to activate in vitro transcriptional activity of the serum response element. Alternative splicing results in multiple transcript variants.
Spécificité tissulaire
Expressed in liver, skeletal muscle, prostate, uterus, rectum, stomach, and bladder and to a lower extent in brain, kidney, pancreas, and bone marrow. Expressed in mononuclear leukocytes and megakaryocytes.
Similitudes de séquence
Belongs to the small GTPase superfamily. Ras family.
Modification post-traductionnelle
Palmitoylated. Palmitoylation is required for association with recycling endosome membranes and activation of TNIK.
Localisation cellulaire
Cytoplasm. Recycling endosome membrane.
