Nsp1p est un gène codé par le symbole NSP1. Communément appelé aussi: Nucleoporin NSP1; Nuclear pore protein NSP1; Nucleoskeletal-like protein; p110; NSP1. Nsp1p a une masse de 86.52kDa et une longueur d'acide aminé de 823.
Nous proposons 1 des anticorps contre Nsp1p, élevé dans Souris, qui sont appropriés pour le WB, IHC, ICC/IF et IP avec des échantillons dérivés de S. cerevisiae.
Informations sur les Gènes et les Protéines
Résumé UniProt
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm). NSP1 plays an important role in several nuclear transport pathways including poly(A)+ RNA, tRNA, pre-ribosome, signal recognition particle (SRP), and protein transport.
Similitudes de séquence
Belongs to the nucleoporin NSP1/NUP62 family.
Localisation cellulaire
Nucleus > Nuclear pore complex. Nucleus membrane. Nucleus membrane.
Symmetric distribution.
