NPY5R est un gène codé par le symbole NPY5R. Communément appelé aussi: Neuropeptide Y receptor type 5; NPY5-R; NPY-Y5 receptor; NPYY5-R; NPYR5. NPY5R a une masse de 50.73kDa et une longueur d'acide aminé de 445.
Nous proposons 9 des anticorps contre NPY5R, élevé dans Lapin et Chèvre, qui sont appropriés pour le WB, IHC, ELISA, ICC/IF et IP avec des échantillons dérivés de Humain, Souris, Rat et Hamster.
Informations sur les Gènes et les Protéines
Résumé UniProt
Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.
Résumé Entrez
The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene.
Spécificité tissulaire
Brain; hypothalamus.
Similitudes de séquence
Belongs to the G-protein coupled receptor 1 family.
Localisation cellulaire
Cell membrane.
