Muscarinic Acetylcholine Receptor 1 est un gène codé par le symbole CHRM1. Communément appelé aussi: Muscarinic acetylcholine receptor M1; CHRM1. Muscarinic Acetylcholine Receptor 1 a une masse de 51.42kDa et une longueur d'acide aminé de 460.
Nous proposons 6 des anticorps contre Muscarinic Acetylcholine Receptor 1, élevé dans Lapin et Chèvre, qui sont appropriés pour le WB, IHC, ELISA et ICC/IF avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Résumé Entrez
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
Similitudes de séquence
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM1 sub-subfamily.
Localisation cellulaire
Cell membrane. Cell junction > Synapse > Postsynaptic cell membrane.
