MMP10 est un gène codé par le symbole MMP10. Communément appelé aussi: Stromelysin-2; SL-2; Matrix metalloproteinase-10; MMP-10; Transin-2; STMY2. MMP10 a une masse de 54.15kDa et une longueur d'acide aminé de 476.
Nous proposons 10 des anticorps contre MMP10, élevé dans Lapin, qui sont appropriés pour le WB, IHC, ELISA et ICC/IF avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.
Résumé Entrez
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11.
Similitudes de séquence
Belongs to the peptidase M10A family.
Localisation cellulaire
Secreted > Extracellular space > Extracellular matrix.
