Mannose Receptor est un gène codé par le symbole MRC1. Communément appelé aussi: Macrophage mannose receptor 1; MMR; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Human hMR; Macrophage mannose receptor 1-like protein 1; MRC1; CLEC13D; CLEC13DL; MRC1L1. Mannose Receptor a une masse de 166.01kDa et une longueur d'acide aminé de 1456.
Nous proposons 18 des anticorps contre Mannose Receptor, élevé dans Lapin, Souris et Rat, qui sont appropriés pour le WB, IHC, ELISA, ICC/IF, Cytométrie en Flux et IP avec des échantillons dérivés de Humain, Souris et Rat.
Informations sur les Gènes et les Protéines
Résumé UniProt
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.
Résumé Entrez
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.
Localisation cellulaire
Endosome membrane. Cell membrane.
